ASP-9521 Size:2mg solid 6'-dichlorophenylamino)-2-imidazoline

6'-dichlorophenylamino)-2-imidazoline

FC1C=C(C=C(F)C=1CN1CCOCC1)C1=CC=CC2=NC=C(N=C21)C1C=NN(C=1)C1CCNCC1

5-3(6)1-2-4(7)8/h4-17

single dose) treatment in mice and rats does not result in toxicity in either species

but also displays marked antiproliferative effects in cell lines with HER2 expressed weakly with IC50 of 53 nM

ASP-9521 Size:2mg solid 6'-dichlorophenylamino)-2-imidazolineASP 9521 is a selective, orally bioavailable inhibitor of 17beta hydroxysteroid dehydrogenase type 5 (17 HSD5). Product information CAS Number: 1126084 37 4 Molecular Weight: 330. 42 Formula: C19H26N2O3 Chemical Name: 1 [1 (5 methoxy 1H indole 2 carbonyl)piperidin 4 yl] 2 methylpropan 2 ol Smiles: CC(C)(O)CC1CCN(CC1)C(=O)C1=CC2C=C(C=CC=2N1)OC InChiKey: OXSCPDKUZWPWFR UHFFFAOYSA N InChi: InChI=1S C19H26N2O3 c1 19(2,23)12 13 6 8 21(9 7 13)18(22)17 11 14